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Effectiveness of Kratom for Opioid Withdrawal Relief

Effectiveness of Kratom for Opioid Withdrawal Relief

Kratom is an herbal supplement used to self-treat opioid withdrawal symptoms. It can lead to side effects in high doses or combined with other substances.

Kratom for Opioid Withdrawal

Relieving opioid withdrawal is crucial, especially since 85% of opioid users experience distressing symptoms like nausea, muscle aches, and insomnia. These discomforts highlight the urgent need for relief. 

Originating from Southeast Asia, kratom offers hope as a natural remedy. With its dual function as both a stimulant and a sedative, kratom presents a promising solution for easing withdrawal symptoms. 

Join us as we explore how kratom can address the challenges of opioid withdrawal, examining its effectiveness and benefits closely.

Understanding Opioid Withdrawal Symptoms

Recognizing opioid withdrawal symptoms is crucial as they vary from physical discomfort to psychological distress. Here are the common symptoms:


Opioid withdrawal often causes excessive tearing or a runny nose. This happens because opioids suppress the body's natural fluid production, and when they're stopped, fluids are produced in excess.

"Goose Flesh"

Piloerection, also known as 'goosebumps,' often occurs during opioid withdrawal. It happens because the body's sympathetic nervous system becomes more active when opioids are stopped. This makes the hair stand up and gives the skin a bumpy texture.

Muscle Pain

Muscle pain is a frequent complaint during opioid withdrawal. Without opioids to suppress pain signals, individuals experience heightened sensitivity, leading to widespread muscle aches.


Diarrhea is a prevalent gastrointestinal symptom of opioid withdrawal. The sudden increase in gastrointestinal activity causes frequent bowel movements.


Nausea and vomiting are common symptoms during opioid withdrawal. Changes in digestive processes without opioids present can lead to discomfort and vomiting.

Pupillary Dilation

Enlarged pupils are a distinctive sign of opioid withdrawal. When opioids are withdrawn, pupils may dilate significantly due to increased sympathetic nervous system activity.


Difficulty sleeping is frequent during opioid withdrawal. Changes in neurotransmitter activity disrupt the sleep-wake cycle, leading to insomnia and daytime fatigue.

Autonomic Hyperactivity

Opioid withdrawal can cause overstimulation of the autonomic nervous system, leading to symptoms such as rapid breathing, increased heart rate, sweating, elevated blood pressure, and elevated body temperature.


Excessive yawning is observed in opioid withdrawal. Changes in neurotransmitter activity lead to frequent yawning as the body adjusts to the absence of opioids.

If you or someone you know is experiencing any of these symptoms, please consult your healthcare provider immediately.

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The Potential of Kratom for Opioid Withdrawal Relief

The potential of kratom for opioid withdrawal relief has attracted significant attention in recent years.

What is Kratom?

Kratom, originating from Southeast Asia, is valued for its adaptable leaves. However, its misuse for relaxation or euphoria is becoming more common. It possesses dual effects, acting as both a stimulant and an opioid-like substance, providing boosts in energy and alertness alongside pain relief and relaxation. Despite its traditional medicinal usage, kratom can induce adverse effects, ranging from mild, such as nausea and drowsiness, to severe, including high blood pressure, seizures, and slowed breathing.

How Does Kratom Work?

Kratom works by interacting with receptors in the brain and body, particularly opioid receptors. Its main active compounds, mitragynine and 7-hydroxy mitragynine, bind to these receptors. This interaction can lead to various effects, including pain relief, relaxation, and increased energy. However, the exact mechanisms of how kratom works and its overall impact on health are still not fully understood, and more research is needed to clarify its effects and potential risks.

Dosage and Administration of Kratom for Opioid Withdrawal

Understanding the proper dosage and administration methods for kratom is crucial for managing opioid withdrawal effectively. You should consult trusted healthcare providers for guidance on kratom usage.

Recommended Kratom Dosage for Withdrawal

For opioid withdrawal relief, kratom dosage varies depending on individual needs and reactions. Lower doses (1-5 grams) typically result in stimulant effects, while higher doses (5-15 grams) may have sedative effects. However, due to kratom's variability and lack of standardized dosing, caution is necessary. Withdrawal symptoms can persist after the last dose, so consulting a healthcare provider familiar with kratom is advisable to determine suitable dosages.

Forms of Kratom Administration

Kratom can be taken in several ways, making it convenient for users. It comes in capsules for easy and precise dosing or as a powder that can be mixed into food or drinks. Some people brew kratom leaves as tea, while others prefer a liquid extract for quicker effects. These different methods cater to individual preferences and provide flexibility in consumption.

Potential Risks and Considerations for Kratom Use

Kratom, often praised for its possible benefits, also poses risks users need to know. Here are some key considerations:


The chemical compounds in kratom, particularly mitragynine and 7-OH-mitragynine, can induce sedative effects similar to opioids. This may result in drowsiness or lethargy, impairing daily activities and alertness.


Kratom use may lead to nausea and vomiting. These symptoms can be unpleasant and may interfere with appetite and overall well-being.


Like traditional opioids, kratom can cause constipation, leading to discomfort and potential digestive issues. Increased fiber intake and hydration are often recommended to alleviate this side effect.

Physical Dependence

Prolonged kratom use can result in physical dependence, where individuals experience withdrawal symptoms upon discontinuation. Symptoms may include agitation, anxiety, insomnia, and flu-like symptoms, highlighting the addictive potential of kratom.

Respiratory Depression

In severe cases, kratom use has been associated with respiratory depression, a potentially life-threatening condition where breathing becomes dangerously slow or shallow. This risk underscores the importance of cautious use and medical supervision when consuming kratom.

Comparing Kratom to Traditional Opioid Withdrawal Treatments

Comparing kratom to traditional opioid withdrawal treatments involves considering their effectiveness and safety. While traditional treatments like methadone or buprenorphine are widely researched and supervised by medical professionals, kratom's benefits and risks are less understood. Some people may turn to kratom for its perceived natural and accessible qualities, but its legal status and varying quality raise concerns. 

It's important to consult a healthcare provider familiar with both options to make an informed choice about opioid withdrawal treatment.

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Our team will call you to answer any questions you have or to help you schedule an appointment.

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Kratom for Opioid Withdrawal FAQs

What are the side effects of taking kratom?

Side effects of taking kratom include nausea, constipation, drowsiness, and dizziness. More severe reactions can lead to high blood pressure, seizures, and slowed breathing.

What drugs interact with kratom?

Kratom can interact with drugs like opioids, benzodiazepines, and antidepressants, which might increase the risk of harmful effects or overdose. It's important to be careful when using kratom with these medications, as it can make their effects stronger.

What are the positive effects of kratom?

Kratom can provide pain relief, boost energy levels, and induce relaxation, but effects may differ from person to person. While some individuals may experience these benefits, others may not feel the same effects. It's important to recognize that individual responses to kratom may vary.

Can kratom be used as a long-term solution for opioid withdrawal management?

While some use kratom for opioid withdrawal relief, its long-term effectiveness lacks strong research evidence. Extended kratom use may lead to dependence or adverse effects. It's essential to be cautious and seek advice from healthcare professionals when considering kratom for withdrawal management.

Find Comfort and Care with Confidant Health

Finding the right solution for opioid withdrawal can feel overwhelming, but at Confidant Health, we're here to provide the support you need for opioid withdrawal management.

Our expert team offers personalized guidance for managing withdrawal symptoms and exploring treatment options. Whether you're considering medication-assisted treatment or other approaches, we'll be with you every step of the way. Plus, with our virtual services, you can receive care from the comfort of your home

You don't have to face this journey alone. Reach out to Confidant Health today, and let us help you find relief and support as you work towards recovery.

This article has been medically reviewed by
Erin Hillers
Erin Hillers
Erin Hillers
Nurse Practitioner

Erin is a Nurse Practitioner with 8 years of experience in midwifery and women's health. She has spent the past 5 years specializing in the treatment of opioid and alcohol use disorders.

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