Naltrexone, an opioid antagonist, is FDA-approved for treating Alcohol Use Disorder (AUD) and Opioid Use Disorder (OUD). Its active end-product, 6-beta-naltrexol, binds to and occupies opioid receptors. As a result, opioids cannot bind to their receptors and produce the feelings of euphoria that substance misusers are seeking. This discourages opioid and alcohol misuse.
In this article, the experts at Confidant Health break down when is the best time for you to take Naltrexone. Read on to learn more.
When Should You Take Naltrexone?
Manufacturers do not appoint one specific time of day as being better than another to take Naltrexone. Thus, users can decide when is the best time to take Naltrexone, based on their preferences and lifestyle.
Why you may Prefer to Take Naltrexone in the Morning
Some users prefer to take Naltrexone in the morning. Here’s why:
- Pairing your dose of Naltrexone with breakfast makes it easier to remember. This means fewer missed doses and better results.
- Naltrexone can aid weight loss. Studies show Naltrexone can reduce appetite by up to 30%. This means that taking it early in the morning can help reduce food cravings throughout the day and enable you to lose weight.
- Research shows Naltrexone can cause insomnia (difficulty falling and staying asleep) in 10% of users. This is because Naltrexone decreases the release of endorphins (or feel-good hormones) by suppressing opioid activity. As a result, the body may not be able to adequately relax for sleep. So, taking Naltrexone in the morning may better suit users who experience difficulty sleeping.
Why you may Prefer to Take Naltrexone at Night
Some users choose to take Naltrexone at night for many reasons; some of these include:
- Some users report daytime sleepiness when taking Naltrexone. Thus, patients that operate heavy machinery during the day should take the medication at night.
- Studies show that low-dose Naltrexone may relieve pain and symptoms of chronic fatigue syndrome. It achieves this by suppressing the release of chemicals (cytokines) that cause pain. So, people with chronic fatigue syndrome may sleep more comfortably if they take Naltrexone before bed.
- 90% of men in a clinical trial experienced sexual dysfunction while taking Naltrexone. To avoid the potential impact of these symptoms, most male users prefer taking the medication right before they sleep.
Who Should Take Naltrexone With Food?
Gastrointestinal disturbances, such as nausea and vomiting, can affect up to 15% of Naltrexone users. Luckily, patients can minimize these symptoms by taking Naltrexone with food.